The hypereosinophilic syndrome revisited.

نویسندگان

  • Florence Roufosse
  • Elie Cogan
  • Michel Goldman
چکیده

Clinical and biological features of patients with the idiopathic hypereosinophilic syndrome (HES) are heterogeneous. Recent evidence suggests at least two distinct underlying hematological disorders involving myeloid and lymphoid cells, respectively. We therefore suggest that the term idiopathic should be abandoned in the classification of HES. This review defines the "myeloproliferative" and "lymphocytic" variants of the HES and addresses the management of each variant, focusing on diagnosis and treatment of the newly identified lymphocytic variant.

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عنوان ژورنال:
  • Annual review of medicine

دوره 54  شماره 

صفحات  -

تاریخ انتشار 2003